Glucose or sucrose solution is normally indicated for babies up to four months of age and generally considered more effective the younger the infant. J. Paediatr. Oral sucrose is a simple sugar solution. Published by Elsevier Ltd. All rights reserved. Stevens B, Yamada J, Ohlsson A. Sucrose analgesia in newborn infants undergoing painful procedures. Oral sucrose is a mild analgesic which is effective in decreasing short-term pain and distress during minor procedures. St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3). This paper explores the foundation and evidence behind eight sucrose myths, providing the reader with current evidence with which to base practice upon, with the aim of improving pain management during painful procedures for both sick and healthy infants. There is a large body of evidence demonstrating the analgesic efficacy of oral sucrose during minor painful procedures in young infants. Use of sucrose has been widely studied for procedural pain in the neonatal intensive care unit and in the newborn nursery settings, particularly for venous blood sampling, capillary blood tests, and circumcision. The aim of this study was to evaluate the effectiveness of oral sucrose in decreasing pain during minor procedures in infants of 1-6 months corrected age. By continuing you agree to the use of cookies. Are there any side effects? Despite this evidence, sucrose is not utilized in many settings for management of acute procedural pain (Harrison, D., et al. The study says that small doses of oral sucrose do not reduce the pain which a baby feels when its heel is pricked to yield a blood sample or it has a drip put in to receive antibiotics. the baby sucrose and the rationale for doing so. Once non-pharmacological measures have been implemented, oral sucrose analgesia may be used in babies in Level II NICU and the Parent Infant Nursery. Administration 22. The present short study of 6-11 month-old infants showed that the difference between means of NIPS score of the study group of sucrose solution and control group of sterile water is statistically very significant (P< 0.001) and oral sucrose solution is thus recommended as a feasible means of minimizing pain of vaccination by injection. Wash hands and use alcohol gel as per local unit policy. Many factors may play a role in this poor uptake of research findings in the clinical setting. Oral sucrose water, generally at a 24% to 25% concentration, seems to provide significant adjunctive pain relief to infants undergoing immunization, the mechanism of action is thought to involve activation of the endogenous opioid system through taste that act as opioid analgesic. Pain assessment and procedural pain management practices in neonatal units in Australia. Oral sucrose is frequently given to relieve procedural pain in neonates on the basis of its effect on behavioural and physiological pain scores. Call 1-866-278-5833 (TTY: 1-901-595-1040), St. Jude Children's Research Hospital - Homepage, For updates to our current visitor policy regarding COVID-19, please, Influenza Center for Excellence & WHO Collaborating Center, Disclaimer / Registrations / Copyright Statement, Venipuncture (taking blood samples from a vein), Lumbar punctures (taking fluid from the spinal cord), Bone Marrow Aspiration (taking sample of liquid marrow from the bone), Bone Marrow Biopsy (taking out a small piece of solid marrow from the bone), Circumcisions (removing foreskin from penis), The child has problems with digesting food or liquids, The child must be NPO, without food and water before a procedure, (may have up to 2 hours before procedure), The child is paralyzed or has a breathing tube, The child has necrotizing enterocolitis (NEC), a disease that destroys part of the intestine, The child has grade 3 or 4 mucositis, which causes ulcers and pain in the mouth and digestive tract, The child has diabetes (high blood sugar), The child is receiving inotropic drug therapy for heart problems. ATENCIÓN: si habla español, tiene a su disposición servicios gratuitos de asistencia lingüística. More Pharmacy & Medicines Education Sheets. Breastfeeding during immunization should be offered to women and their babies routinely as a pain avoidance procedure. It is given on the tongue or inside the cheek, and the action of sucking on a pacifier is thought to increase the effect of sucrose. A pacifier may be inserted after the drops are given. 2006. Conclusion: Oral sucrose was effective in reducing behavioural responses to pain upon heel lance and in the period following completion of a heel lance procedure in this group of sick hospitalized infants. Oral sucrose has a beneficial role in pain prevention and management for infants, including babies in the emergency department.7,8Although most research on oral sucrose has been conducted in newborn nurs-eries and neonatal intensive care units (NICUs), we present 2 case reports that illustrate use of oral sucrose in pediatric and cardiac We use cookies to help provide and enhance our service and tailor content and ads. On this basis, Slater and colleagues conclude that oral sucrose is ineffective for pain relief in infants, and discourage its routine use in infants. Call: 1-888-226-4343 Fax: 901-595-4011 Email: referralinfo@stjude.org Online: Referral Form Physician / Patient Referral Office. Infants excluded from receiving oral sucrose include those with carbohydrate metabolism disorders (such as fructose or sucrose intolerance), and disruption to the integrity of oral mucosa, due to diagnosed yeast infection, oral surgery/trauma and mucositis. Oral sucrose is safe and effective for reducing procedural pain from a single event. One of these factors may be what the author of this paper has termed, sucrose myths; i.e. To give sucrose to your baby, squeeze it out onto a pacifier, or squirt it into the side of your baby's cheek. https://doi.org/10.1016/j.jnn.2007.12.002. Oral sucrose will not always eliminate all crying, but is known to significantly reduce the physiological stress of pain. A Solution to Calm & Soothe Babies. Oral sucrose should be combined with other comfort measures, such as holding and swaddling the infant, position changes, and distraction. 1, 3 Although randomized controlled trials (RCTs) evaluating effects of sucrose in infants were not published until the late 1980s, there are historical references pertaining to the analgesic and calming benefits of sweet substances dating back to ad 632, when Prophet Mohammed … It is given on the tongue or inside the cheek, and the action of sucking on a pacifier is thought to increase the effect of sucrose. Copyright © 2021 Elsevier B.V. or its licensors or contributors. St. Jude Graduate School of Biomedical Sciences, Volunteer at the Hospital Become a Monthly Donor. 1 Small amounts of sweet solutions (oral sucrose) are placed on the infant's tongue to reduce procedural pain. If used as directed, sucrose does not have any side effects. Sweet-Ease is a 24% sucrose and purified water solution that helps to calm and soothe infants. Goodfellow Gems Oral sucrose a good analgesic for infant immunizations. A pediatrician should decide the use of sugar water or sweet sucrose water for relieving the baby’s pain after a medical procedure. Oral sucrose compares favourably with lidocaine-prilocaine cream for pain relief during venepuncture in neonates. Correspondence Oral sucrose for that sucrose has long-term negative at the midbrain owing to its ability to effects.5 We agree with Slater and “inhibit facial motor activity”. Reduction of pain in prematures using oral sucrose. Become a monthly donor and receive a shirt, Information for our supporters in response to COVID-19. ®. ATTENTION: If you speak another language, assistance services, free of charge, are available to you. Babies 6 months and younger can have oral sucrose. We assessed whether sucrose administration reduces pain-specific brain and spinal cord activity after an acute noxious procedure in newborn infants. Recommended dosage is typically correlated to patient weight up to 3kg, with a full 2ml ampoule appropriate above 3kg. Oral sucrose has analgesic and calming properties in infant. Copyright © 2007 Neonatal Nurses Association. It is commonly used prior to and during procedures that may cause discomfort to the infant.†. Oral sucrose is a mild analgesic which is safe and effective in decreasing short-term pain and distress during minor procedures. ® "Do you know..." is an educational series for patients and their families. The sugar cane is grown without pesticides, herbicides or artificial fertilizers of any kind…and since it’sRead More The sweetness of breast milk has proven to be as effective as a pain-relieving … We identified high-quality evidence that sucrose reduces pain for heel lance, venipuncture and intramuscular injection. Although sucrose has been widely studied as a pain reliever for newborn babies, most studies have included few babies and have used many different measures of pain to assess its effectiveness. Parents must avoid its use for pacifying the baby in general. The use of oral sucrose, with or without pacifiers, has been shown to relieve pain in neonates, as assessed by physiologic and behavioral pain indicators and pain scores. In this randomized controlled trial, during immunization, 120 babies up to six months old were randomized to breastfeeding, oral sucrose, or the usual comforting measures. procedural pain in colleagues that every effort should be “Absence of evidence of effect in infants made to minimise nociceptive path- this study”, does not mean evidence way activation in infants. Check patient identity as … Sweet-ease® for Infant Pain Relief Sweet-ease® is an oral liquid made of sugar (sucrose) and water that can be used to decrease pain in infants. Our aim is to promote active participation in your care and treatment by providing information and education. Check 24% sucrose pack is undamaged and within shelf life. It is safe to use for all babies 12 months and younger, except babies who are premature, and with low birth weight, and unstable sugar levels. 23. Sweet-ease® may be used if your baby is going to the operating room or having deep sedation in the sedation clinic to complete a painful procedure. Sucrose as an analgesic for newborn infants. More than 150 published studies relating to sweet-taste-induced calming and analgesia in human infants have been identified, of which 100 (65%) include sucrose. Acta Paediatr 2001;90(2):160-5. Our product is made of USDA certified organic sucrose. تنبيه: إذا كنت تتحدث باللغة العربية فيمكنك الاستعانة بخدمات المساعدة اللغوية المتوفرة لك مجانا. ExploreTogether, an online resource for anyone facing childhood cancer. Therefore, use it only when required. If you speak another language, assistance services, free of charge, are available to you. Oral sucrose or other sweet tasting solutions in small volumes (0.05-1 mL) combined with non-nutritive sucking is effective in reducing pain in infants during minor procedures. Measures of pain were lower in the breastfeeding group. Abad F, Diaz-Gomez NM, Domenech E, et al. Llame al 1-866-278-5833 (TTY: 1-901-595-1040). The aliquot volume will be influenced by the infant’s weight and maximum dose per procedure (refer to above table). Thank you for your support and understanding. You do so much to protect babies. No more than 3 ml should be given within an 8 hour time frame. SweetUms is a 24% Sucrose Solution to help calm and soothe babies. Check the sucrose prescription, as per network guideline.. Ascertain whether sucrose is to be given with a pacifier. A blinded randomized controlled trial with infants aged 4-26 weeks who underwent venipuncture, heel lance or intravenous cannulation were stratified by corrected age into >4-12 weeks and >12-26 weeks. Herschel M, Khoshnood B, Ellman C, Maydew N, Mittendorf R. Neonatal circumcision: randomized trial of a sucrose pacifier for pain control. 24% Oral Sucrose has been widely studied and proven to help reduce discomfort in infants. Call 1-866-278-5833 (TTY: 1-901-595-1040). Its proven effectiveness as an analgesic, low rate of minor adverse events, ease of administration, and excellent availability make sucrose a good choice for this purpose. Questions about individual health concerns or specific treatment options should be discussed with your physician. The sweetness of breast milk has proven to be as effective as a pain relieving strategy. Saving children. This document is not intended to take the place of the care and attention of your personal physician or other professional medical services. Oral: Two minutes prior to the anticipated painful procedure, use the syringe to administer an aliquot of the Sucrose dose slowly onto the front of the infant’s tongue. Arch Dis Childh 1996;78:126-28. Oral sucrose is safe and effective for reducing minor procedural pain from single events like heel prick, intramuscular injection and venepuncture. IMPLICATIONS FOR PRACTICE: Oral sucrose solution should be used as a pain reduction intervention in infants up to 12 months of age undergoing minor painful procedures.